Guidance on Pre-Exposure Prophylaxis (PrEP) for Serodiscordant Couples, Men and Transgender Women Who Have Sex with Men at High Risk of HIV: Recommendations for Use in the Context of Demonstration Projects

Pre-exposure prophylaxis (PrEP) is effective in preventing HIV transmission. Oral PrEP has been evaluated in gay men and other men who have sex with men, transgender women, heterosexual men and women and people who inject drugs. This guidance is intended to complement WHO recommendations (2012) and support the optimal use of oral PrEP to protect individuals and contribute to ending the AIDS epidemic.